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The addition of Constant Current Mode for measuring electrophoretic mobility and zeta potential in high conductivity media reduces errors that can be associated with electrode polarization at higher ion concentrations. The information provided by these measurements is an excellent indicator of sample stability and/or propensity to aggregate. Our affordable disposable folded capillary cells enable measurements in extremely low volumes, without direct sample-electrode contact, using our patented diffusion barrier method. The Zetasizer Ultra also provides the highest sensitivity zeta potential and electrophoretic mobility measurements using M3-PALS technology. This is a unique capability of the Zetasizer Ultra which can even be applied to samples such as viruses and VLPs, which were previously very challenging to measure. The measurement of particle concentration is calibration-free, suitable for a wide range of materials, requires no or little dilution, and is quick to use – all of which make it ideal as a screening technique. NIBS provides the versatility and sensitivity to measure over a wide concentration range, while MADLS permits a higher resolution view into your sample’s size distribution for those critical measurements.Īn extension to MADLS affords the ability to directly analyze particle concentration. The Zetasizer Ultra is the world’s most capable combined DLS and ELS system, incorporating Non-Invasive Back Scatter (NIBS ®) and, uniquely, Multi-Angle Dynamic Light Scattering (MADLS) technology for the measurement of particle and molecular size. The Malvern Materials Talks are of substantial help, similar webinars." Would be great to simply switch to laser wavelengths which is not exciting fluorophores.Īlthough DLS/ZP measurements are very straightforward to do on the ZS Ultra, continuous education is needed to become proficient. Malvern may consider offering the ZS Ultra with two laser wavelengths in the same instrument! We have troubles sometimes with fluorescently labeled species and strong fluorescence reaching the detectors - the filter in front of the BS detector is not sufficient to eliminate all fluorescence if strong emitters are investigated. The Tech Support from Ulf Nobbmann is excellent, mostly available and feedback is always on the point. The new cuvette allows particle size measurements to be made using.
#Malvern zetasizer di software#
The newest software version (V2.0+) does not run on our lap PC and so far nobody could resolve it. Malvern Instruments has introduced a new disposable sample cuvette for its Zetasizer systems. Way too many steps, Malvern should find a better solution. Data transfer to a server or between two PCs is not user-friendly at all. Maybe it would be an advantage to be able to split graphs and tables into two different monitors for a better overview and quicker data analysis. The selection of the data display parameters and measurement conditions are not well accessible/presentable. For example, one can only save ONE custom configuration of data displays, but each user has its own preferences and needs. The "Measure" menu is easy to use, but the data analysis is not well outlined. The system is robust and little instructions are needed for newcomers to DLS/ZP. We are also using the Zeta Potential technique to measure surface charges, mainly for nanoparticles and surface-modified nanoparticles. Pengukuran ini menggunakan metode Dynamic Light Scattering dengan sistem backscattering 173°. The Zetasizer Nano ZS90 is the perfect lower cost solution when the ultimate in sizing sensitivity is not necessary, or where identical results to a legacy system with 90 degree scattering optics is required." The Zetasizer Ultra is a very useful instrument for our R&D activities as we can measure sizes of antibodies and other proteins, assess their aggregation status, and determine also approximate concentrations using the 3 angle measurement capabilities. menggunakan fasilitas MALVERN Zetasizer Nano ZS. The ZSP also incorporates a zeta potential analyzer that uses electrophoretic light scattering for particles, molecules and surfaces, and a molecular weight analyzer using static light scattering. The Zetasizer Nano ZS is a high performance two angle particle and molecular size analyzer for the enhanced detection of aggregates and measurement of small or dilute samples, and samples at very low or high concentration using dynamic light scattering with ‘NIBS’ optics. The Zetasizer Nano Z is the perfect system for measuring zeta potential and electrophoretic mobility of colloids and nanoparticles, when the measurement of size or molecular weight is not required. The Zetasizer Nano S90 is the perfect lower cost solution when the ultimate in sizing sensitivity is not necessary, or where identical results to a legacy system with 90 degree scattering optics are required. It has the same sizing capability as the top of the range The Zetasizer Nano S is the system of choice where the highest sensitivity and widest size range is required.